Publications:
Harrison, T.E.*, Alam, N.*, Farrell, B.*, Quinkert, D., Lias, A.M., King, L.D., Draper, S.J., Campeotto, I. and Higgins, M.K. (2024) Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5. EMBO Molecular Medicine 16 2539-59 (* contributed equally)
Wang, L.T.*, Cooper, A.*, Farrell, B.*, Miura, K., Diouf, A., Muller-Sienerth, N., Crosnier, C., Purser, L., Maciuszek, M., Barret, J.R., McHugh, K., Tucker, C., Li, S., Doumbo, S., Doumtabe, D., Pyo, C.-P., Nielsen, C.M., Silk, S.E., Kayentao, K., Ongoiba, A., Nguyen, D.C., Lee, F.E., Minassian, A.M., Geraghty, D.E., Traore, B., Seder, R.A., Crompton, P.D., Wright, G., Draper, S.J., Long, C., Higgins, M.K. and Tan, J. (2023) Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5. Cell 187 4981-95 (* contributed equally)
Farrell, B., Alam, N., Hart, M.N., Jamwal, A., Ragotte, R.J., Walters-Morgan, H., Draper, S.J., Knuepfer, E. and Higgins, M.K.* (2023) The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 578-584
Farrell B, Breeze AL. (2018) Structure, activation and dysregulation of fibroblast growth factor receptors: perspectives for clinical targeting. Biochem Soc Trans, 46: 1753-1770. DOI: 10.1042/BST20180004
Sanfelice D, Koss H, Bunney TD, Thompson GS, Farrell B, Katan M, Breeze AL. (2018) NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074. Biomol NMR Assign, 12: 231-235. DOI: 10.1007/s12104-018-9814-7
Bunney TD, Inglis AJ, Sanfelice D*, Farrell B*, Kerr CJ, Thompson GS, Masson GR, Thiyagarajan N, Svergun DI, Williams RL, Breeze AL, Katan M. (2018) Disease variants of FGFR3 reveal molecular basis for the recognition and additional roles for Cdc37 in Hsp90 chaperone system. Structure, 26: 446-458. DOI: 10.1016/j.str.2018.01.016
ORCID ID: 0000-0001-9919-9141