Higgins Lab : All Pages

• Welcome to the website of the Higgins lab
• Our discoveries
• Who we are
• Parasite Stories
• News
• Publications
• Nawsad Alam
• Sam Gérard
• Frank Lennartz
• Abhishek Jamwal
• Matt Higgins
• Tom Harrison
• Natalie Barber
• How do trypanosome receptors bind transferrin?
• Congratulations Dr Natalie Barber!
• Designer Malaria vaccines at the IF science festival
• Understanding the human antibody response to RH5 vaccination
• A broadly neutralising PvDBP-targeting antibody to block vivax malaria
• Alyssa Crabb
• Understanding how RH5 interacts with basigin and inhibitory antibodies
• Designing a thermally stabilised RH5
• How do malaria infected erythrocytes bind to EPCR?
• Dual ICAM1 and EPCR binding PfEMP1 proteins and cerebral malaria
• Conservation and diversity in CD36-binding PfEMP1 proteins
• An unusual LAIR1-containing antibody
• The structure of the trypanosome haptoglobin-haemoglobin receptor
• Evolutionary divergence of the trypanosome haptoglobin-haemoglobin receptor
• Understanding a malaria transmission blocking antibody
• Trypanosome work highlighted in the Diamond annual review 2019
• Investigating what makes an African trypanosome human infective
• Harriet Lane-Serff
• Kate Wright
• Alan Brown
• Clinton Lau
• Ivan Campeotto
• Fu-Lien Hsieh
• Jon Bartlett
• Two strategies for survival used by trypanosome receptors
• What do antibodies teach us about how to stop blood stage malaria?
• An eon in the life of a trypanosome receptor
• A family affair: understanding a parasite surface protein family
• Brendan Farrell
• Re'em Moskovitz
• Dan Alanine
• How do trypanosomes evade destruction by binding factor H?
• How do malaria parasites regulate the LILRB1 inhibitory immune receptor?
• Alex Cook
• The inhibited conformation of the Sec translocon
• Wellcome Investigator Award to fund the Higgins lab
• Kuang-Ting Ko
• Malhar Khushu
• Riming Huang
• Clare Wolfle
• Understanding the architecture of the Plasmodium-interspersed repeat proteins
• Congratulations Dr Tom Harrison
• Malaria work highlighted in Diamond Annual Review 2020
• Sam Gerard tells EMBO workshop about inhibited Sec translocon structure
• Richard Zhou
• Sam Chamberlain
• Hannah Walters-Morgan
• Hannah Ivison
• Wright Medal of the British Society for Parasitology
• Bora Guloglu
• First Class grades and a Biochemical Society Award for project students
• Poy (Tossapol) Pholcharee
• Stephan Hirschi
• A novel mechanism of antibody synergy mediated through lateral interactions
• Structure of transmission-blocking malaria vaccine candidate Pfs48/45
• Alex Cook speaks at the British Society for Parasitology spring meeting
• Our malaria vaccine work highlighted by AlphaFold
• How do trypanosomes resist killing by the complement system?
• How do neutralising antibodies prevent erythrocyte invasion in malaria?
• Congratulations to Dr Sam Gerard
• Visualising a bridge between a malaria parasite and a human erythrocyte that occurs during erythrocyte invasion
• Matt is awarded the EP Abraham Chair of Structural Biology
• Understanding an essential interaction required for red blood cell invasion in malaria caused by Plasmodium vivax
• How does ISG65 help trypanosomes resist complement?
• Kuang-Ting and Brendan appearing at BioMalPar XIX
• Higgins lab receives a Silver LEAF award
• Egle Butkeviciute
• Irvinder Wason
• How do helminth parasites block allergic responses in asthma?
• Matthew Clark
• Manan Pant
• Understanding the molecular machinery which enables the malaria parasite to invade blood cells
• Aneilia Simpson
• Oxford Mosaic Accessibility Statement
• How do naturally occurring antibodies recognise the malaria vaccine candidate PfRH5?
• Brian Amabilino
• Beth Bakewell-Smith
• Congratulations to Dr Poy Pholcharee
• Brendan Farrell wins poster prize at BCA winter meeting
• Structure-guided design of an epitope-focused malaria vaccine
• Higgins Lab: Use of cookies on this website
• Congratulations Dr Bora Guloglu
• RIFINs bind to inhibitory and activating KIR immune receptors
• Poster prize and talk at a wonderful BioMalPar 2024
• Structure-guided design of a vaccine immunogen against Plasmodium vivax
• Mariah Lofgren
• Designing the RH5.2 malaria vaccine immunogen
• Malaria Vaccines
• How does the deadly amoeba, Entamoeba histolytica bind to our cells?
• Daisy Pendergast
• Dara Thaker
• Emily Egerton-Warburton
• Congratulations Dr Kuang-Ting Ko
• Congratulations to Dr Richard Zhou
• Scavenger receptor CD163 multimerises to allow uptake of diverse ligands
• Designer Malaria Vaccines
• Talk prize for Sam at UK Natural Killer cell meeting