Higgins Lab : All Pages
Welcome to the website of the Higgins lab
Who we are
How do trypanosome receptors bind transferrin?
Congratulations Dr Natalie Barber!
Designer Malaria vaccines at the IF science festival
Understanding the human antibody response to RH5 vaccination
A broadly neutralising PvDBP-targeting antibody to block vivax malaria
Understanding how RH5 interacts with basigin and inhibitory antibodies
Designing a thermally stabilised RH5
How do malaria infected erythrocytes bind to EPCR?
Dual ICAM1 and EPCR binding PfEMP1 proteins and cerebral malaria
Conservation and diversity in CD36-binding PfEMP1 proteins
An unusual LAIR1-containing antibody
The structure of the trypanosome haptoglobin-haemoglobin receptor
Evolutionary divergence of the trypanosome haptoglobin-haemoglobin receptor
Understanding a malaria transmission blocking antibody
Trypanosome work highlighted in the Diamond annual review 2019
Investigating what makes an African trypanosome human infective
Two strategies for survival used by trypanosome receptors
What do antibodies teach us about how to stop blood stage malaria?
An eon in the life of a trypanosome receptor
A family affair: understanding a parasite surface protein family
How do trypanosomes evade destruction by binding factor H?
How do RIFINs bind to LILRB1?
The inhibited conformation of the Sec translocon
Wellcome Investigator Award to fund the Higgins lab
Understanding the architecture of the Plasmodium-interspersed repeat proteins
Congratulations Dr Tom Harrison
Malaria work highlighted in Diamond Annual Review 2020
Sam Gerard tells EMBO workshop about inhibited Sec translocon structure
Wright Medal of the British Society for Parasitology
First Class grades and a Biochemical Society Award for project students
Poy (Tossapol) Pholcharee
A novel mechanism of antibody synergy mediated through lateral interactions
Structure of transmission-blocking malaria vaccine candidate Pfs48/45
Alex Cook speaks at the British Society for Parasitology spring meeting
Our malaria vaccine work highlighted by AlphaFold
How do trypanosomes resist killing by the complement system?
How do neutralising antibodies prevent erythrocyte invasion in malaria?
Congratulations to Dr Sam Gerard
Visualising a bridge between a malaria parasite and a human erythrocyte that occurs during erythrocyte invasion
Matt is awarded the EP Abraham Chair of Structural Biology
Understanding an essential interaction required for red blood cell invasion in malaria caused by Plasmodium vivax
How does ISG65 help trypanosomes resist complement?
Kuang-Ting and Brendan appearing at BioMalPar XIX
Higgins lab receives a Silver LEAF award
How do helminth parasites block allergic responses in asthma?
Understanding the molecular machinery which enables the malaria parasite to invade blood cells
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How do naturally occurring antibodies recognise the malaria vaccine candidate PfRH5?