Ivan Campeotto

Ivan Campeotto spent four years with us as a postdoctoral research fellow. He led our program of structure-guided design for RH5-based vaccine components. An early success was the thermal stabilisation of RH5, generating a molecule which can be more easily produced and with increased stability. More to come as his later designs are still in pre-clinical testing!

In 2018 Ivan moved to the University of Leicester to start his own research program and in April 2020 he started a lectureship at Nottingham Trent University. In 2022 he moved to take up an Associate Professorship at the University of Nottingham (https://www.nottingham.ac.uk/biosciences/people/ivan.campeotto).

Publications while in the Higgins lab:

Campeotto, I., Goldenzweig, A., Davey, J., Barfod, L., Marshall, J.M., Silk, S.E., Wright, K.E., Draper, S.J., Higgins, M.K.* and Fleishman, S.J.* (2017) One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen. Proc Natl Acad Sci U S A. 114 998-1002

Warszawski, S., Dekel, E., Campeotto, I., Marshall, J.M., Wright, K.E., Lyth, O., Knop, O., Regev-Rudzki, N., Higgins, M.K., Draper, S.J., Baum, J. and Fleishman, S.J. (2019) Design of a basigin-mimicking inhibitor targeting the malaria invasion protein RH5. Proteins doi: 10.1002/prot.25786

Harrison, T.E., Alam, N., Farrell, B., Quinkert, D., Lias, A.M., King, L.D., Draper, S.J., Campeotto, I. and Higgins, M.K.* (2024) Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5. https://doi.org/10.1101/2024.02.29.582763 (* equal corresponding)