Kuang-Ting Ko

I graduated from National Tsing Hua University, Taiwan, with an M.Sc. degree in Bioinformatics and Structural Biology. Under the supervision of Prof. Ping-Chiang Lyu and Dr. Shang-Te Danny Hsu in the master project, I constructed circular permutants of a knotted protein called YbeA to study the folding properties and structural effects of untying a topological knot in a protein. Afterwards, I worked as a research assistant in Dr. Shang-Te Danny Hsu’s lab in Academia Sinica, Taiwan, studying a complex structure of p97, an AAA+ ATPase, with a stress-induced adaptor protein using Cryo-EM.

My experience in solving crystal structures captivated my interest in structural biology. I will like to apply techniques to study the protein-protein interactions and structures in innate immune system when infected by pathogens.