Matt studied Natural Sciences at Christ’s College, University of Cambridge, where he specialised in Biochemistry and was awarded a first-class degree.
His graduate studies were conducted at the MRC Laboratory of Molecular Biology in Cambridge, with Dr Nigel Unwin, where he used electron microscopy to study ion channels and clathrin lattice formation.
He remained in Cambridge for his post-doctoral studies, where he used protein crystallography to characterise bacterial antibiotic efflux pumps and components of the vision system.
In 2006 he was awarded a Royal Society University Research Fellowship to establish a research team to study the molecular basis for host-parasite interactions in malaria. He moved to Oxford in 2010 as a University Lecturer and was promoted to Professor of Molecular Parasitology in 2015 and was appointed Tutorial Fellow at Merton College.